Synthetic and Systems Biology

Engineering & Social Sciences Program
Madrid, Spain

Dates: mid Jan 2026 - early Jun 2026

Engineering & Social Sciences

Synthetic and Systems Biology

Synthetic and Systems Biology Course Overview

OVERVIEW

CEA CAPA Partner Institution: Universidad Carlos III de Madrid
Location: Madrid, Spain
Primary Subject Area: Biomedical Engineering
Instruction in: English
Course Code: 14162
Transcript Source: Partner Institution
Course Details: Level 400
Recommended Semester Credits: 3
Contact Hours: 42
Prerequisites: It is strongly advised to have completed Cell and Molecular Biology, Biochemistry, Bioinformatics.

DESCRIPTION

Gene and protein sequencing, gene expression analysis, protein expression and interaction analysis, genomic and proteomic analysis . protein-protein Interaction networks, metabolic networks and disease networks, quantitative tissue analysis, modeling biological systems: synthetic biology circuits, data analysis techniques and clinical computing interfaces.

The course is divided mainly in two parts:
SYSTEMS BIOLOGY AND OMIC TECHNOLOGIES:
- Fundamentals of genomics, proteomics and metabolomics
- How do normal cellular functions such as cellular division, cell activation, differentiation, and apoptosis emerge from the interaction of genes
- How to examine whole cell functions corresponding to observable phenotypes.
- How to generate network reconstructions, followed by the synthesis of in silico models describing functionalities.
- Systems Analysis of Complex Diseases.
- Systems Pharmacology: Understanding Drug Action from a System Perspective.
- Systems Pharmacogenomics: Personalized medicine.

SYNTHETIC BIOLOGY:
- Design and construction of new biological parts, devices, and systems, and the re-design of existing natural biological system for better application.
- Build artificial biological systems for engineering applications.
- Draw powerful techniques for the rapid assembly of DNA.
- Engineer biological system: modify the behaviour of organisms and engineer them to perform new tasks. Create bioengineered microorganisms that can produce pharmaceuticals and repair damaged genes.


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