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Current topics in Molecular and Cellular Toxicology- Period 5
STEM in Amsterdam Program
Amsterdam, Netherlands
Dates: 1/31/20 - 6/27/20
Current topics in Molecular and Cellular Toxicology- Period 5
OVERVIEW
CEA CAPA Partner Institution: Vrije Universiteit Amsterdam
Location: Amsterdam, Netherlands
Primary Subject Area: Biology
Instruction in: English
Course Code: XB_0010
Transcript Source: Partner Institution
Course Details: Level 300
Recommended Semester Credits: 3
Contact Hours: 84
Prerequisites: Cellulaire Biochemie, Bio-analyse en farmaceutische toxicology, Farmacokinetiek & ADME-processen
DESCRIPTION
Subjects of this course/caput are optional and may vary, depending on the rest of the program and/or the interest of the BSc-student(s). In close cooperation with the teaching coordinator, several topics will be chosen, focusing on induced pluripotent stem cells (iPSC), ADMET and using stem cells for assessment of toxicity.
Detailed description:
The course will consist of lectures about iPSC generation and application for toxicity study and personalized medicine, as well as about basic developmental biology and basic physiology of target organs in toxicity (liver, kidney and other). The students will then do an assignment based on literature search with topics identified in the course. Topics may vary and could for example be based on a polymorphism in a gene involved in ADMET which may result in altered efficacy and toxicity profiles.
Contact hours listed under a course description may vary due to the combination of lecture-based and independent work required for each course therefore, CEA's recommended credits are based on the ECTS credits assigned by VU Amsterdam. 1 ECTS equals 28 contact hours assigned by VU Amsterdam.
Detailed description:
The course will consist of lectures about iPSC generation and application for toxicity study and personalized medicine, as well as about basic developmental biology and basic physiology of target organs in toxicity (liver, kidney and other). The students will then do an assignment based on literature search with topics identified in the course. Topics may vary and could for example be based on a polymorphism in a gene involved in ADMET which may result in altered efficacy and toxicity profiles.
Contact hours listed under a course description may vary due to the combination of lecture-based and independent work required for each course therefore, CEA's recommended credits are based on the ECTS credits assigned by VU Amsterdam. 1 ECTS equals 28 contact hours assigned by VU Amsterdam.