Structure Biology - Period 5

Central to this course are molecular properties of structural elements of DNA, lipids and proteins. The forces and interactions that determine their structure, function and flexibility will be discussed. The basics and applications of a number of techniques used to experimentally determine macromolecular structures as well as techniques to visualize dynamic structural changes will also be introduced. This includes crystallization followed by X-ray diffraction, NMR spectroscopy and electron microscopy. Also, the principles and applications of computational structure determination (protein modeling) will be discussed.

Contact hours listed under a course description may vary due to the combination of lecture-based and independent work required for each course therefore, CEA's recommended credits are based on the ECTS credits assigned by VU Amsterdam. 1 ECTS equals 28 contact hours assigned by VU Amsterdam.