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CEA CAPA Partner Institution: Universidad Carlos III de Madrid
Location: Madrid, Spain
Primary Subject Area: Biomedical Engineering
Instruction in: English
Course Code: 14162
Transcript Source: Partner Institution
Course Details: Level 400
Recommended Semester Credits: 3
Contact Hours: 42
Prerequisites: It is strongly advised to have completed Cell and Molecular Biology, Biochemistry, Bioinformatics.
DESCRIPTION
Gene and protein sequencing, gene expression analysis, protein expression and interaction analysis, genomic and proteomic analysis . protein-protein Interaction networks, metabolic networks and disease networks, quantitative tissue analysis, modeling biological systems: synthetic biology circuits, data analysis techniques and clinical computing interfaces.
The course is divided mainly in two parts: SYSTEMS BIOLOGY AND OMIC TECHNOLOGIES: - Fundamentals of genomics, proteomics and metabolomics - How do normal cellular functions such as cellular division, cell activation, differentiation, and apoptosis emerge from the interaction of genes - How to examine whole cell functions corresponding to observable phenotypes. - How to generate network reconstructions, followed by the synthesis of in silico models describing functionalities. - Systems Analysis of Complex Diseases. - Systems Pharmacology: Understanding Drug Action from a System Perspective. - Systems Pharmacogenomics: Personalized medicine.
SYNTHETIC BIOLOGY: - Design and construction of new biological parts, devices, and systems, and the re-design of existing natural biological system for better application. - Build artificial biological systems for engineering applications. - Draw powerful techniques for the rapid assembly of DNA. - Engineer biological system: modify the behaviour of organisms and engineer them to perform new tasks. Create bioengineered microorganisms that can produce pharmaceuticals and repair damaged genes.
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