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Principles of Systems Biology- Period 1
Computer Science Program
Amsterdam, Netherlands
Dates: mid Aug 2025 - late Dec 2025
Principles of Systems Biology- Period 1
OVERVIEW
CEA CAPA Partner Institution: Vrije Universiteit Amsterdam
Location: Amsterdam, Netherlands
Primary Subject Area: Biology
Instruction in: English
Course Code: X_428566
Transcript Source: Partner Institution
Course Details: Level 300
Recommended Semester Credits: 3
Contact Hours: 84
DESCRIPTION
Theoretical topics:
- The two branches of systems biology
- Data structure, geometrical mapping, PCA, distance metrics, clustering
- Cellular composition, diffusion, time scales, rates
- Mass-action, mass balances, reactions, equilibria, stable/unstable steady states equilibrium binding, affinity, conformational change, ultrasensitivity, transduction cascades, autoregulation, mutual inhibition/activation, bistability, feed-forward loops, steady state metabolism, regulation of metabolism and regulation by demand
Practical:
- Exercises during/in between lectures in which methods of systems biology will be applied to several topics.
- Conversion classes
Depending on their background, students will also be assigned to one out of three deficiency classes where they will be working to fill gaps in their knowledge in mathematics, programming and/or biology.
Contact hours listed under a course description may vary due to the combination of lecture-based and independent work required for each course therefore, CEA's recommended credits are based on the ECTS credits assigned by VU Amsterdam. 1 ECTS equals 28 contact hours assigned by VU Amsterdam.
- The two branches of systems biology
- Data structure, geometrical mapping, PCA, distance metrics, clustering
- Cellular composition, diffusion, time scales, rates
- Mass-action, mass balances, reactions, equilibria, stable/unstable steady states equilibrium binding, affinity, conformational change, ultrasensitivity, transduction cascades, autoregulation, mutual inhibition/activation, bistability, feed-forward loops, steady state metabolism, regulation of metabolism and regulation by demand
Practical:
- Exercises during/in between lectures in which methods of systems biology will be applied to several topics.
- Conversion classes
Depending on their background, students will also be assigned to one out of three deficiency classes where they will be working to fill gaps in their knowledge in mathematics, programming and/or biology.
Contact hours listed under a course description may vary due to the combination of lecture-based and independent work required for each course therefore, CEA's recommended credits are based on the ECTS credits assigned by VU Amsterdam. 1 ECTS equals 28 contact hours assigned by VU Amsterdam.