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Synthetic and Systems Biology
Engineering & Social Sciences Program
Madrid, Spain
Dates: 1/16/25 - 6/4/25
Synthetic and Systems Biology
OVERVIEW
CEA CAPA Partner Institution: Universidad Carlos III de Madrid
Location: Madrid, Spain
Primary Subject Area: Biomedical Engineering
Instruction in: English
Course Code: 14162
Transcript Source: Partner Institution
Course Details: Level 400
Recommended Semester Credits: 3
Contact Hours: 42
Prerequisites: It is strongly advised to have completed Cell and Molecular Biology, Biochemistry, Bioinformatics.
DESCRIPTION
Gene and protein sequencing, gene expression analysis, protein expression and interaction analysis, genomic and proteomic analysis . protein-protein Interaction networks, metabolic networks and disease networks, quantitative tissue analysis, modeling biological systems: synthetic biology circuits, data analysis techniques and clinical computing interfaces.
The course is divided mainly in two parts:
SYSTEMS BIOLOGY AND OMIC TECHNOLOGIES:
- Fundamentals of genomics, proteomics and metabolomics
- How do normal cellular functions such as cellular division, cell activation, differentiation, and apoptosis emerge from the interaction of genes
- How to examine whole cell functions corresponding to observable phenotypes.
- How to generate network reconstructions, followed by the synthesis of in silico models describing functionalities.
- Systems Analysis of Complex Diseases.
- Systems Pharmacology: Understanding Drug Action from a System Perspective.
- Systems Pharmacogenomics: Personalized medicine.
SYNTHETIC BIOLOGY:
- Design and construction of new biological parts, devices, and systems, and the re-design of existing natural biological system for better application.
- Build artificial biological systems for engineering applications.
- Draw powerful techniques for the rapid assembly of DNA.
- Engineer biological system: modify the behaviour of organisms and engineer them to perform new tasks. Create bioengineered microorganisms that can produce pharmaceuticals and repair damaged genes.
The course is divided mainly in two parts:
SYSTEMS BIOLOGY AND OMIC TECHNOLOGIES:
- Fundamentals of genomics, proteomics and metabolomics
- How do normal cellular functions such as cellular division, cell activation, differentiation, and apoptosis emerge from the interaction of genes
- How to examine whole cell functions corresponding to observable phenotypes.
- How to generate network reconstructions, followed by the synthesis of in silico models describing functionalities.
- Systems Analysis of Complex Diseases.
- Systems Pharmacology: Understanding Drug Action from a System Perspective.
- Systems Pharmacogenomics: Personalized medicine.
SYNTHETIC BIOLOGY:
- Design and construction of new biological parts, devices, and systems, and the re-design of existing natural biological system for better application.
- Build artificial biological systems for engineering applications.
- Draw powerful techniques for the rapid assembly of DNA.
- Engineer biological system: modify the behaviour of organisms and engineer them to perform new tasks. Create bioengineered microorganisms that can produce pharmaceuticals and repair damaged genes.